Anti-Tumor Necrosis Factor-α Induced Systemic Lupus Erythematosus

Anti-Tumor Necrosis Factor-α Induced Systemic Lupus Erythematosus§

Anti-tumor necrosis factor-alpha induced lupus (ATIL) represents a major diagnostic and therapeutic challenge. Most cases of ATIL are caused by infliximab, followed by etanercept and adalimumab. Symptoms can range from common, mild cutaneous lesions to rare, serious pleural or pericardial effusions, deep venous thrombosis, life-threatening pneumonitis, and neuritis. Constitutional symptoms ofte...

Anti-Tumour Necrosis Factor-α Induced Systemic Lupus Erythematosus

On anti-tumor necrosis factor-induced systemic lupus erythematosus.

Induction of systemic lupus erythematosus with tumor necrosis factor blockers.

Systemic lupus erythematosus induced by anti-tumour necrosis factor alpha therapy: a French national survey

The development of drug-induced lupus remains a matter of concern in patients treated with anti-tumour necrosis factor (TNF) alpha. The incidence of such adverse effects is unknown. We undertook a retrospective national study to analyse such patients. Between June and October 2003, 866 rheumatology and internal medicine practitioners from all French hospital centres prescribing anti-TNF in rheu...